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KMID : 0861020170320030009
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Korea Journal of Herbology
2017 Volume.32 No. 3 p.9 ~ p.17
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Lipid Improvement Effect of New manufacturing method produced Kyeongok-go on hyperlipidemia rats
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Choe Ung-Sik
Ku Ga-Ram
Lee Ah-Reum
Kwon Oh-Jun
Seo Young-Bae
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Abstract
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Objectives： Kyeongok-go has the effect of antioxidant, anti-cancer, improving fatigue, and hyperlipidemia, but it is not easy to use in clinical practice becausee of the complicated manufacturing process of heat control and moisture control. The aim of this study was to explore the lipid improvement effect of new manufacturing methods prodeced Kyeongok-go in hyperlipidemia rats.
Methods : The SD rats were divided randomly into 8 groups of six animals each : Normal rats (Nor), hyperlipidemia rats (Con), hyperlipidemia rats treated with Spirulina 60 ㎎/㎏(SP60), hyperlipidemia rats treated with Commercial Kyeongok-go 1 g/㎏ (K0), hyperlipidemia rats treated with Kyeongok-go manufactured by heating mantle 1 g/㎏ (K1), hyperlipidemia rats treated with ginseng fermentation Kyeongok-go 1 g/㎏ (KF), hyperlipidemia rats treated with Kyeongok-go with black ginseng 1 g/㎏ (BK), hyperlipidemia rats treated with black ginseng fermentation Kyeongok-go 1 g/㎏ (BKF). The experimental group induced hyperlipidemia by eating high cholesterol diet for 8 weeks. Also, we compared Kyeongok-go manufacturing method using the new method compared with traditional method.
Results : As a result, the improvement effect of hyperlipemia using the new method showed the similar or better improvement effect compared with the conventional method, and it is considered that the Kyeongok-go manufacturing method using the new method can be substituted for the traditional Kyeongok-go manufacturing method.
Conclusion : In conclusion, these results suggest that new manufacturing methods prodeced Kyeongok-go has the potential as a anti-hyperlipidemia material which possess lipid improvement activities.
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KEYWORD
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Kyeongok-go, new mabufacturing method, heating Mentle, black ginseng, hyperlipidemia
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